Alpha 2 Macroglobulin Injection Therapy – A New Treatment of Osteoarthritis
Alpha 2 Macroglobulin Injection Therapy Miami – is the newest biologic treatment in our regenerative medicine practice. It can be successfully applied for the management of arthritic and degenerative conditions, such as Osteoarthritis (OA), which is one of the most common health problems, with nearly 30 million Americans suffering with this disease.
Alpha 2 Macroglobulin, or A2M injection therapy, uses proven scientific techniques and natural healing methods to successfully treat osteoarthritis at its source. It is used to prevent cartilage breakdown in patients, promote tissue growth and support the overall restoration of an affected joint, like the knee.
Contact us to know more about Alpha 2 Macroglobulin Injection Therapy in Miami.
What is A2M (Alpha 2 Macroglobulin) ?
A2M stands for Alpha 2 Macroglobulin, which is a naturally occurring protein found in blood plasma. However, A2M is not a platelet product; A2M circulates in the plasma portion of your blood.
PRP, for example, does not have A2M in it. Though your blood has some A2M, concentrated A2M can only be accomplished by a special concentrator.
By collecting your blood and processing it through a multi-phase centrifugation and filtration system, a concentrated volume of A2M can be collected. This selectively super concentrates A2M.
A2M acts as an inhibitor of a wide variety of proteinases, which are enzymes that break down proteins. In particular, it’s A2M’s ability to inhibit the action of Matrix Metalloproteinases (MMPs) that may make it useful as a possible treatment for arthritis.
The A2M produced by the concentrator can then be used for treatment inside of joints, degenerative discs, and into damaged soft tissues and areas of inflammation.
Scientific evidence for A2M efficacy
Scientific evidence points to A2M to be the key to stopping osteoarthritis at the molecular level. A2M is a Broad Spectrum Multi-Purpose Protease Inhibitor (powerful chemical in destroying proteins that cause arthritis) that captures and inactivates the three major chemicals that lead to joint breakdown and cartilage damage.
Once these bad chemicals are trapped by A2M, the body can then quickly eliminate them. A joint injection of concentrated A2M provides cartilage protection in Osteoarthritis by stopping the progression of arthritis.
Not all joints respond to A2M but there is an excellent test to identify joints that will likely do well with an A2M treatment. This test is called fibronectin-aggrecan G3 complex test (FAC). It specifically identifies significant levels of the very specific protein which is highly diagnostic for arthritis. If one has this protein, then treatment with A2M may be of benefit.
Concentrated A2M injections – results of the research studies:
The results of research studies suggest that a therapeutic injection of concentrated A2M may inhibit the breakdown of cartilage and shut down the destructive inflammatory proteins in the joint.
Additionally, it is noted that early intervention may be critical for preventing or minimizing the development of post-traumatic Osteoarthritis (OA). An injection of A2M during the acute phase of an injury is proving to be a powerful tool in preventing progressive arthritis in the affected joints.
This can be especially powerful in preventing arthritis which often occurs after an ACL repair in the knee joint. In addition, there is data suggesting that there is also a regenerative component to A2M which can further help the joint, spinal disc or soft tissue recover.
The A2M protein is made in your liver.
All along, while you have been experiencing pain from an injury, or just normal wear and tear, you have been carrying around the cure! The A2M protein is made in your liver. Using special binding sites, it will bind and trap bad enzymes that are destroying your cartilage. Once each of A2M’s binding sites is occupied, the A2M and the disabled enzymes are removed by your body naturally. This is called suicide inhibition.
Due to its large size, A2M cannot make it into the joint in high enough concentrations in certain circumstances, which may lead to chronic pain, and collapse of the joint. This new technology allows doctors to use a highly concentrated injection of Alpha 2 Macroglobulin to absorb the enzymes trying to digest cartilage.
A2M in Miami – a potent treatment for osteoarthritis
A2M Injection Therapy is becoming an integral part of our regenerative treatments and a complete biologics program for the restoration of joints, prevention of knee and other joint arthritis and the treatment of low back pain.
In addition to A2M Injection treatments for osteoarthritis, we are using A2M injections as an adjunct to stem cell injections in order to optimize the environment and maximize the potential success of our stem cell therapy.
Alpha 2 Macroglobulin Injection Therapy Miami (A2M Miami) – more information
Alpha 2 Macroglobulin (A2M) uses the most advanced science to not only stop osteoarthritis at its source, but also protect you from a protein complex that causes your joints to ache.
To find out more about A2M Injection therapy in Miami and if this treatment will be suitable for your condition, please don’t hesitate to contact us. We will be happy to assist you.
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