Saliva hormones more accurately reflect tissue uptake and response of hormones delivered through the skin in creams or patches. Urine and blood assays significantly underestimate hormones delivered topically, often resulting in overdosing. If you use topical hormone applications, saliva analysis can most effectively monitor these therapies.
Salivary hormone analysis represents what is clinically relevant and conveys a patient’s true hormonal activity, and is an easy and excellent way to obtain multiple samples.
Salivary diagnostics hold great promise as an effective option for the early diagnosis, prognostication, and monitoring of therapy. Whole saliva is a mixture of the secretions of the major and minor salivary glands, mucosal transudations, gingival crevicular fluid, serum and blood derivatives from oral wounds, desquamated epithelial cells, expectorated bronchial and nasal secretions, bacteria and bacterial products, viruses and fungi, other cellular components, and food debris. It is a complex fluid containing an entire library of hormones, proteins, enzymes, antibodies, antimicrobial constituents, and cytokines. Promising new technologies have unveiled large numbers of medically valuable salivary biomarkers for different disease conditions including cancer, autoimmune, viral, bacterial, cardiovascular, and metabolic diseases
